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Biology and medicine are being revolutionized
by the advent of new technologies. The data emerging from
the Human Genome Project and other organisms resulted in
the emergence of new disciplines of science collectively
called as 'OMICS Science' (genomics, proteomics, metabolomics
and pharmacogenomics). They offer new solutions to the unresolved
problems in complex diseases. 'OMICS' studies result in
production of huge amount of data in terms of sequence,
structure, gene expression, proteins, metabolites and function.
The aim of this course is to impart training in the analysis
of genomics and proteomics data. It covers topics related
to molecular biology, genome analysis, functional and structural
genomics, recombinant DNA technology, and DNA & protein
sequence data analysis. The course includes several experiments
in wet-lab and computational methodologies.
Many biotech and pharmaceutical organizations are trying
to analyze such data to produce new targets using in-silico
tools. However, their efforts are limited by the shortage
of skilled man power. This course has been designed to address
such a need.
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Duration
4 Months (3 hours per day, 6 days a week)
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Methodology
Instructor Led Training (ILT) |
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Man to Machine
Ratio : 1:1
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Who
can do this course
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Ph.Ds
in any science discipline. |
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Postgraduates
with specialization in any of the areas
of molecular biology, genetics, microbiology,
structural biology, chemistry, veterinary
sciences, food sciences, agricultural sciences
and biotechnology. |
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B.Pharm, M.Pharm,
MBBS, MD, BE/B.Tech, ME/M.Tech etc. |
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Graduates in
any science discipline. |
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Course Contents |
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Molecular biology |
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Recombinant DNA Technology
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Genome Projects and Genome
Analysis |
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DNA & Protein Sequence Anallysis
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Genomics - Functional/Structural
genomics |
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Microarray and Proteomics
data Analysis |
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Metobolomic
Pathways |
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Pharmacogenomics
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Project Work |
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Wet-lab: |
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A set of gene cloning experiments
starting from isolation of genomic DNA and vector
DNA to expression of the cloned gene. Isolation of
genomic DNA, isolation and purification of vector
DNA, restriction enzyme digestion of genomic and vector
DNA, ligation of vector and genomic DNA fragments,
transformation of bacteria and selection of recombinants,
selection of clones expressing the gene, Southern,
Northern and Western blotting, and polymerase chain
reaction. In-silico: Genome analysis, microarray data
analysis, proteome data analysis, DNA/ protein sequence
analysis using GCG Wisconsin Package, pharmacogenomics,
data mining and metabolic pathways.
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